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Summary of Effects of Atomoxetine and Placebo on ADHD Symptoms in Adults* |
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| Study I |
Study II |
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|
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| Placebo (n = 134) |
Atomoxetine (n = 133) |
p |
Placebo (n = 124) |
Atomoxetine (n = 124) |
p |
|
|
|
|
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| CGI Change Score |
-0.4 ± 1.0 |
-0.8 ± 1.2 |
0.010 |
-0.5 ± 1.0 |
-0.9 ± 1.2 |
0.002 |
| Investigator-Rated CAARS |
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| Total ADHD Symptom Scores |
-6.0 ± 9.3 |
-9.5 ± 10.1 |
0.005 |
-6.7 ± 9.3 |
-10.5 ± 10.9 |
0.002 |
| Inattentive Score |
-3.1 ± 5.8 |
-5.0 ± 5.7 |
0.010 |
-3.5 ± 5.3 |
-5.8 ± 6.5 |
0.001 |
| Hyperactive/Impulsive Score |
-2.9 ± 4.9 |
-4.5 ± 5.1 |
0.017 |
-3.2 ± 4.7 |
-4.7 ± 5.3 |
0.013 |
| Self-Rated CAARS |
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| Total ADHD Symptom Score |
-9.3 ± 14.0 |
-16.0 ± 16.2 |
0.002 |
-11.6 ± 16.1 |
-17.3 ± 17.6 |
0.008 |
| Inattentive Score |
-8.6 ± 13.8 |
-15.9 ± 16.3 |
0.001 |
-11.3 ± 16.6 |
-17.1 ± 17.9 |
0.012 |
| Hyperactive/Impulsive Score |
-7.5 ± 12.1 |
-11.9 ± 13.5 |
0.013 |
-8.8 ± 13.4 |
-12.5 ± 14.1 |
0.025 |
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*Data adapted from Michelson et al., 2003 Data are presented as mean ± standard deviation | ||||||
Faraone et al. Behavioral and Brain Functions 2005 1:16 doi:10.1186/1744-9081-1-16 |
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