Table 1

Allele frequencies


All affecteds*
 SCZ + SA
SNP ID (dbSNP No)
 Alleles (major/minor) *
 MAF Controls
 MAF Cases
 p-value
 Trend p-value
 OR (95%CI)
 MAF Controls
 MAF Cases
 p-value
 Trend p-value
 OR (95%CI)


n = 467
 n = 394


n = 467
 n = 258


rs2097063 (287A/G)
 A/G
 0.414
 0.346
 0.004
 0.006
 1.34 (1.10, 1.64)
 0.414
 0.347
 0.015
 0.019
 1.33 (1.06, 1.67)
rs737865
 T/C
 0.309
 0.332
 0.315
 0.321
 1.11 (0.90, 1.37)
 0.309
 0.329
 0.438
 0.448
 1.10 (0.87, 1.39)
rs4680 (Val/Met)
 A/G
 0.475
 0.524
 0.050
 0.048
 1.21 (1.00, 1.47)
 0.475
 0.504
 0.304
 0.299
 1.12 (0.90, 1.40)
rs165599
 A/G
 0.326
 0.376
 0.035
 0.040
 1.25 (1.02, 1.53)
 0.326
 0.364
 0.160
 0.175
 1.18 (0.94, 1.49)


SCZ
 Affective disorder*
SNP ID (dbSNP No)
 Alleles (major/minor) *
 MAF Controls
 MAF Cases
 p-value
 Trend p-value
 OR (95%CI)
 MAF Controls
 MAF Cases
 p-value
 Trend p-value
 OR (95%CI)


n = 467
 n = 196


n = 467
 n = 112


rs2097063 (287A/G)
 A/G
 0.414
 0.338
 0.011
 0.014
 1.39 (1.08, 1.79)
 0.414
 0.346
 0.062
 0.067
 1.34 (0.98, 1.82)
rs737865
 T/C
 0.309
 0.327
 0.511
 0.518
 1.09 (0.84, 1.41)
 0.309
 0.329
 0.560
 0.556
 1.10 (0.80, 1.50)
rs4680 (Val/Met)
 A/G
 0.475
 0.500
 0.419
 0.414
 1.10 (0.87, 1.41)
 0.475
 0.565
 0.018
 0.015
 1.43 (1.06, 1.93)
rs165599
 A/G
 0.326
 0.362
 0.221
 0.240
 1.17 (0.91, 1.51)
 0.326
 0.400
 0.039
 0.043
 1.38 (1.02, 1.87)


Major depressive disorder
 BP
SNP ID (dbSNP No)
 Alleles (major/minor) *
 MAF Controls
 MAF Cases
 p-value
 Trend p-value
 OR (95%CI)
 MAF Controls
 MAF Cases
 p-value
 Trend p-value
 OR (95%CI)


n = 467
 n = 30


n = 467
 n = 82


rs2097063 (287A/G)
 A/G
 0.414
 0.283
 0.046
 0.049
 1.79 (1.01, 3.18)
 0.414
 0.369
 0.280
 0.290
 1.21 (0.86, 1.71)
rs737865
 T/C
 0.309
 0.333
 0.688
 0.689
 1.12 (0.64, 1.95)
 0.309
 0.327
 0.638
 0.634
 1.09 (0.76, 1.56)
rs4680 (Val/Met)
 A/G
 0.475
 0.586
 0.101
 0.093
 1.56 (0.91, 2.68)
 0.475
 0.557
 0.058
 0.050
 1.39 (0.99, 1.95)
rs165599
 A/G
 0.326
 0.414
 0.169
 0.184
 1.46 (0.85, 2.51)
 0.326
 0.395
 0.088
 0.095
 1.35 (0.96, 1.91)

* All Affecteds: SCZ (schizophrenia), SA (schizoaffective disorder), BP (bipolar disorder), Major depressive disorder, psychotic disorder NOS, depressive disorder NOS

* Affective Disorder: Bipolar disorder and major depressive disorder

Funke et al. Behavioral and Brain Functions 2005 1:19   doi:10.1186/1744-9081-1-19