Table 1

Comparison of age-related long-term effects of a single methamphetamine intoxication on the dopamine innervation in limbocortical areas of the gerbil brain.



Adult (current study) MA 1 × 25 mg/kg i.p., p180
Juvenile [Reference] MA 1 × 50 mg/kg i.p., p14

Prefrontal cortex
Medial
↔ n.s.
↓ – 38% ** [14]

Orbital
↔ n.s.
↓ – 50% ** [14]
Nucleus accumbens
Core
↔ n.s.
↓ – 28% * [15]

Shell
↑ +11% *
↔ n.s. [15]
Amygdala
Basolateral
↔ n.s.
↑ +18% ** [12]

Central
↔ n.s.
↔ n.s. [12]
Olfactory Tubercle

↔ n.s
No data

Significance values: * p < 0.05, ** p < 0.01.

Brummelte et al. Behavioral and Brain Functions 2006 2:12   doi:10.1186/1744-9081-2-12