|
Effect sizes (beta) per minor allele copy for RGS4 gene SNPs |
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| rs10917670 per A allele copy |
rs951436 per G allele copy |
rs2661319 per G allele copy |
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|
|
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| Response |
N |
beta |
Pall-load (PANOVA) |
N |
beta |
Pall-load (PANOVA) |
N |
beta |
Pall-load (PANOVA) |
|
|
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| IQ (RPM) |
1470 |
-0.39 |
0.235 (0.349) |
1595 |
0.17 |
0.603 (0.799) |
1411 |
0.10 |
0.773 (0.715) |
|
|
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| SPQ total score |
1043 |
0.49 |
0.363 (0.607) |
1134 |
-0.65 |
0.215 (0.455) |
1004 |
-0.64 |
0.246 (0.502) |
|
|
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| SPQ cognitive/perceptual factor |
1041 |
0.00 |
0.553 (0.839) |
1132 |
-0.00 |
0.807 (0.966) |
1002 |
-0.00 |
0.514 (0.795) |
|
|
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| SPQ negative factor |
1041 |
0.01 |
0.184 (0.291) |
1132 |
-0.01 |
0.009 (0.031) |
1002 |
-0.01 |
0.039 (0.117) |
|
|
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| SPQ disorganization factor |
1041 |
0.01 |
0.256 (0.493) |
1132 |
-0.01 |
0.266 (0.538) |
1002 |
-0.01 |
0.262 (0.493) |
|
|
|||||||||
| SPQ paranoid factor |
1041 |
0.00 |
0.980 (0.876) |
1132 |
0.00 |
0.908 (0.881) |
1002 |
0.00 |
0.896 (0.976) |
|
|
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| d'-S2B (spatial working memory) |
1434 |
-0.06 |
0.153 (0.352) |
1558 |
-0.02 |
0.514 (0.650) |
1384 |
-0.02 |
0.682 (0.900) |
|
|
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| d'-V2B (verbal working memory) |
1372 |
-0.05 |
0.124 (0.306) |
1494 |
0.02 |
0.556 (0.285) |
1324 |
0.01 |
0.755 (0.785) |
|
|
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| Antisaccade error rate |
1585 |
0.01 |
0.286 (0.565) |
1731 |
-0.01 |
0.069 (0.173) |
1532 |
-0.02 |
0.028 (0.089) |
|
SNP, single nucleotide polymorphism; ANOVA, analysis of variance; Pall-load, p value for the allele-load model; PANOVA, ANOVA p value. Strong linkage disequilibrium was observed between rs10917670 and rs951439 (r2 = 0.98). Results of rs951439 are not shown but are similar to rs 10917670. | |||||||||
Stefanis et al. Behavioral and Brain Functions 2008 4:46 doi:10.1186/1744-9081-4-46 |
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