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MEG event-related desynchronization and synchronization deficits during basic somatosensory processing in individuals with ADHD

Colleen Dockstader1 email, William Gaetz2 email, Douglas Cheyne1,2 email, Frank Wang1 email, F Xavier Castellanos3 email and Rosemary Tannock1,4 email

1Neurosciences and Mental Health Program, The Hospital for Sick Children, Toronto, Canada

2Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada

3Child Study Center, New York University, New York, USA

4Human Development & Applied Psychology, Ontario Institute for Studies in Education, Toronto, Canada

author email corresponding author email

Behavioral and Brain Functions 2008, 4:8doi:10.1186/1744-9081-4-8

Published: 12 February 2008

Additional files

Additional file 1:

Example of a control subject's SAM peak locations and values during control (SAM peak value = 2.0) and active (SAM peak value = 16.3) states in somatosensory cortex

Format: PDF Size: 529KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 2:

Example of an ADHD subject's SAM peak locations and values during control (SAM = 1.3) and active (SAM peak value = 15.0) states in somatosensory cortex

Format: PDF Size: 523KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 3:

Control SI Frequency and Power Dynamics During Predicted versus Random Presentation of a Somatosensory Stimulus (A). Grand Mean TFR of the individual, virtual channel, spatially-filtered single trials for control subjects during Predicted presentation of a stimulus. The plot was baselined using the average spectral energy observed in the pre-stimulus period (-100 – 0 ms). (B) Grand Mean TFR of the individual, virtual channel, spatially-filtered single trials for control subjects during Random presentation of a stimulus. (C) Mean TFR differences between conditions. (D) Statistically significant values remaining once condition differences were thresholded to p </= 0.05.

Format: PDF Size: 566KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 4:

ADHD SI Frequency and Power Dynamics During Predicted versus Random Presentation of a Somatosensory Stimulus (A). Grand Mean TFR of the individual, virtual channel, spatially-filtered single trials for subjects with ADHD during Predicted presentation of a stimulus. The plot was baselined using the average spectral energy observed in the pre-stimulus period (-100 – 0 ms). (B) Grand Mean TFR of the individual, virtual channel, spatially-filtered single trials for subjects with ADHD during Random presentation of a stimulus. (C) Mean TFR differences between conditions. (D) Statistically significant values remaining once condition differences were thresholded to p </= 0.05.

Format: PDF Size: 556KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 5:

Control SII Frequency and Power Dynamics During Predicted versus Random Presentation of a Somatosensory Stimulus (A). Grand Mean TFR of the individual, virtual channel, spatially-filtered single trials for control subjects during Predicted presentation of a stimulus. The plot was baselined using the average spectral energy observed in the pre-stimulus period (-100 – 0 ms). (B) Grand Mean TFR of the individual, virtual channel, spatially-filtered single trials for control subjects during Random presentation of a stimulus. (C) Mean TFR differences between conditions. (D) Statistically significant values remaining once condition differences were thresholded to p </= 0.05.

Format: PDF Size: 574KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 6:

ADHD SII Frequency and Power Dynamics During Predicted versus Random Presentation of a Somatosensory Stimulus (A). Grand Mean TFR of the individual, virtual channel, spatially-filtered single trials for subjects with ADHD during Predicted presentation of a stimulus. The plot was baselined using the average spectral energy observed in the pre-stimulus period (-100 – 0 ms). (B) Grand Mean TFR of the individual, virtual channel, spatially-filtered single trials for subjects with ADHD during Random presentation of a stimulus. (C) Mean TFR differences between conditions. (D) Statistically significant values remaining once condition differences were thresholded to p </= 0.05.

Format: PDF Size: 566KB Download file

This file can be viewed with: Adobe Acrobat Reader


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